The role of epigenetic modifications on the carcinogenesis process has received a lot of attention in the last years.Among MALAT1 inhibits the Wnt/?-catenin signaling pathway in colon cancer cells and affects cell proliferation and apoptosis those, histone acetylation is a process regulated by histone deacetylases (HDAC) and histone acetyltransfera
Development of mine-used flameproof three-phase asynchronous motor with high voltage and high efficiency
In view of problems of energy waste and environmental pollution caused by high power consumption and low efficiency of existing motors, a mine-used flameproof three-phase asynchronous motor with ?????? ??????? ?a ???a?????? ????a?? ? ???????? ?????????. A??? ?a??a????????a ????????????????? ?a??a???a ???? ?????? ???????. high voltage and high effic
Sulfonylureas in type 2 diabetes mellitus: Current evidence, conflicts and clinical implications
INTRODUCTION: We sought to explore the current state of evidence on sulfonylurea therapy in type 2 diabetes mellitus (T2DM) and critically examine the recommendations of major practice guidelines,and the overall ramifications of the issues thereof in current clinical practice.METHOD: We searched PUBMED, MEDLINE and other databases, and selected, an
Demonstration of N,N-Dimethyldithiocarbamate as a Copper-Dependent Antibiotic against Multiple Upper Respiratory Tract Pathogens
ABSTRACT Transition metals are necessary cofactors and structural elements in living systems.Exposure to high concentrations of biologically important transition metals, such as zinc and copper, results in cell toxicity.At the infection site, the immune system deploys metal sorbent Predicting Forex Currency Fluctuations Using a Novel Bio-Inspired M